Minimum system requirements for running Geneious Prime

This depends greatly on the type of work you will be using Geneious Prime for, but we recommend at least the following:

  • Operating System: See Supported Operating Systems
  • Processor: x86/x86_64
  • Memory: 2048MB or more.
  • Hard-disk: 2GB or more of free space.
  • Video: 1024x768 resolution or higher.
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    I am assembling complete organellar genomes. Someone told me that I got to have at 32G RAM to run the assembly in a timely manner.

    I notice that you said the minimum Ram is only 2G. I am wondering whether I could be ok by using a 64bit 4G Ram laptop computer to run my assembly. How slow would it be? 2 days?

    Thank you!

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    Hilary Miller

    Geneious R6 will give you an indication of how much RAM is required when you set up your assembly.  If you don't have enough RAM your assembly won't just be slow, it won't work at all.  In general, assembling genome sequencing data takes more than the minimum RAM required for Geneious, but it depends on the size of your genome, the number of reads you are trying to assemble and whether you have a reference genome. 

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    Are these the same system requirements for R8? It has been over two years since this was posted.

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    Hilary Miller

    Yes, those system requirements are valid for R8.  However, be aware that they are minimum requirements, and you may require more computing power for some analyses or for large datasets.

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    Jason Andras

    Two questions:

    1.  Do multiple processors help?  Does Geneious make use of parallel processing?

    2.  The recommendations at the start of this thread are for minimum system requirements.  Can you suggest some "optimal" or at least "good" system requirements for using Geneious R8 for moderate assembling projects?  Of course more RAM is better, but can you offer some specific suggestions? Would 16G be "good"?  Is 32 G overkill?  64G?  How about processor speed and number of processors?  I know all of these scale depending on the task, but I'd love some suggestions for setting up an overall versatile machine. 

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    Matt Kearse

    No matter what you're doing with Geneious, I'd recommend an SSD as that will help a lot with performance.

    1. Yes multiple processors help in that you can run multiple operations at the same time more efficiently. Only a few areas of Geneious make use of parallel processing during a single operation. For example, for de novo assembly, read mapping and variant finding, these are mult-threaded, so the more processors you have the faster they'll go.

    2. De novo assembly can be very memory intensive. For example, to de novo assemble something the size of the human genome using Velvet, according to you'll probably need around 500 GB of memory. But if you're just working with bacteria, 16 GB will probably be sufficient. If you're just mapping to a human genome and not doing de novo assembly, then 16 GB is OK but you may find 32 GB helps.